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Channel: Comments on: Best Case Ever 28: Anti-NMDA Receptor Encephalitis
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By: Leon Gussow

Super, super discussion of a very important topic. The only thing I’d add is that sometimes these patients, during the psychotic phase, get treated with a neuroleptic agent. This makes it even more...

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By: Anton Helman

Great point Leon. Yet another reason why benzodiazepines are a safer bet for sedation of psychotic patients in the ED.

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By: Osher

I would recommend to determine the NMDAR anti-bodies titers level in CSF and serum, not just determination if its positive or negative, P.S. It can be positive in serum as well not just in CSF

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By: Wes Pierce

These patients may also present with psychomotor agitation and get ketamine, which will further propogate NMDA antagonism. Something to ponder as ketamine gains traction for psychomotor agitation and...

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